H8653
Sigma
(±)-7-Hydroxy-2-(di-n-propylamino)tetralin hydrobromide
| Synonym: | (±)-7-Hydroxy-DPAT hydrobromide, (±)-7-OH-DPAT hydrobromide, (±)-2-Dipropylamino-7-hydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide |
| CAS Number: | 159795-63-8 |
| Linear Formula: | C16H25NO · HBr |
| Molecular Weight: | 328.29 |
| MDL number: | MFCD00153809 |
| PubChem Substance ID: | 24277938 |
Description
| Biochem/physiol Actions | A selective D3 dopamine receptor agonist (Kd <1nM); has much weaker affinity for other dopamine receptor subtypes. |
Properties
| solubility | H2O: 15 mg/mL |
| Gene Information | human ... DRD3(1814) |
| storage temp. | 2-8°C |
Safety
| Personal Protective Equipment | dust mask type N95 (US), Eyeshields, Gloves |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
References
| reference | Caine, S.B., et al., Effects of dopamine D(1-like) and D(2-like) agonists in rats that self-administer cocaine. J. Pharmacol. Exp. Ther. 291, 353, (1999) Abstract |
| Dastur, F.N., et al., Dopaminergic modulation of rat pup ultrasonic vocalizations. Eur. J. Pharmacol. 382, 53, (1999) Abstract | |
| Maj, J., et al., Effect of antidepressant drugs administered repeatedly on the dopamine D3 receptors in the rat brain. Eur. J. Pharmacol. 351, 31, (1998) Abstract |
